Wydawca: Packt Publishing
Tiago Antao
Bioinformatics is an active research field that uses a range of simple-to-advanced computations to extract valuable information from biological data.This book covers next-generation sequencing, genomics, metagenomics, population genetics, phylogenetics, and proteomics. You'll learn modern programming techniques to analyze large amounts of biological data. With the help of real-world examples, you'll convert, analyze, and visualize datasets using various Python tools and libraries.This book will help you get a better understanding of working with a Galaxy server, which is the most widely used bioinformatics web-based pipeline system. This updated edition also includes advanced next-generation sequencing filtering techniques. You'll also explore topics such as SNP discovery using statistical approaches under high-performance computing frameworks such as Dask and Spark.By the end of this book, you'll be able to use and implement modern programming techniques and frameworks to deal with the ever-increasing deluge of bioinformatics data.
Shane Brubaker
If you've ever felt overwhelmed by the vast number of Python tools available for bioinformatics, you're not alone. The Bioinformatics with Python Cookbook is a recipe-based guide that explores practical approaches for solving classic bioinformatics challenges, showing you which Python packages work best for each task.You’ll start with the essential Python libraries for data science and bioinformatics, then move through key workflows in sequencing analysis, quality control, alignment, and variant calling. Along the way, you’ll pick up modern coding practices, explore recent advances in bioinformatics research, and gain hands-on experience with libraries such as NumPy, pandas, and sci-kit learn. This book walks you through core bioinformatics tasks such as phylogenetic analysis and population genomics while familiarizing you with the wealth of modern public bioinformatics databases. You’ll learn cloud computing approaches used by researchers, set up workflow orchestration systems for controlling bioinformatics pipelines, and see how AI and the use of large language models (LLMs) are reshaping the field–right down to designing proteins and DNA.By the end of this book, you’ll be ready to apply Python for real bioinformatics work and launch bioinformatics pipelines for your research.
Tiago Antao
Bioinformatics is an active research field that uses a range of simple-to-advanced computations to extract valuable information from biological data, and this book will show you how to manage these tasks using Python.This updated third edition of the Bioinformatics with Python Cookbook begins with a quick overview of the various tools and libraries in the Python ecosystem that will help you convert, analyze, and visualize biological datasets. Next, you'll cover key techniques for next-generation sequencing, single-cell analysis, genomics, metagenomics, population genetics, phylogenetics, and proteomics with the help of real-world examples. You'll learn how to work with important pipeline systems, such as Galaxy servers and Snakemake, and understand the various modules in Python for functional and asynchronous programming. This book will also help you explore topics such as SNP discovery using statistical approaches under high-performance computing frameworks, including Dask and Spark. In addition to this, you’ll explore the application of machine learning algorithms in bioinformatics.By the end of this bioinformatics Python book, you'll be equipped with the knowledge you need to implement the latest programming techniques and frameworks, empowering you to deal with bioinformatics data on every scale.
Darko Medin
This book leverages the author’s decade-long experience in biostatistics and data science to simplify the practical use of biostatistics with Python. The chapters show you how to clean and describe your data effectively, setting a solid foundation for accurate analysis and proficiency in biostatistical inference to help you draw meaningful conclusions from your data through hypothesis testing and effect size analysis.The book walks you through predictive modeling to harness the power of Python to create robust predictive analytics that can drive your research and professional projects forward. You'll explore clinical biostatistics, learn how to design studies, conduct survival analysis, and synthesize evidence from multiple studies with meta-analysis – skills that are crucial for making informed decisions based on comprehensive data reviews. The concluding chapters will enhance your ability to analyze biological variables, enabling you to perform detailed and accurate data analysis for biological research. This book's unique blend of biostatistics and Python helps you find practical solutions that make complex concepts easy to grasp and apply.By the end of this biostatistics book, you’ll have moved from theoretical knowledge to practical experience, allowing you to perform biostatistical analysis confidently and accurately.
John Ward
BIRT is an Eclipse-based open source reporting system for web applications based on Java and Java EE. To address a wide range of reporting needs within a typical application, ranging from operational or enterprise reporting to multi-dimensional online analytical processing (OLAP), you need to know BIRT from head to toe. If you wish to start making reports easily and quickly, and also want to be up-to-date with the latest developments in BIRT, then this book is for you. It will guide you from scratch to develop reports using the Eclipse BIRT project. You will learn how to connect to data, use report items to display and format data, and use scripting to build advanced reports and charts.The book steers you through each step of report setup, to creating, designing, formatting, and deploying reports with data from a wide range of data sources. Its focus is on familiarizing you with the most visible and familiar product built with the BIRT framework – the BIRT Report Designer. It starts by introducing the concepts of business intelligence and open source software, and different installation methods. It will introduce you to the various visual report elements that can be used to design BIRT reports, such as the Palette and Grid components. You will learn the details of the data components of BIRT (the Data Source and the Data Set), different types of source data that BIRT supports such as XML files, flat text files, and databases, and the creation of all of the elements while connecting to Data Sources in reports and Report Projects. By the end of the book, you will be able to enhance the presentation of your report using Charts, Hyperlinks, and Drill Through. You will also be able to take advantage of the scripting capabilities that BIRT has to offer with Expressions and Event Handlers and successfully deploy BIRT reports.The book includes a case study at the end along with a real-world example that runs throughout the book.
Albert Szmigielski
Blockchain is being billed as the technology of the future. Bitcoin is the first application of that technology. Mining is what makes it all possible. Exploring mining from a practical perspective will help you make informed decisions about your mining setup. Understanding what the future may hold for blockchains, and therefore for mining, will help you position yourself to take advantage of the impending changes.This practical guide starts with an introduction to Bitcoin wallets, as well as mining hardware and software. You will move on to learn about different mining techniques using the CPU, GPU, FPGA, and ultimately the ASIC as an example. After this, you will gain an insight into solo mining and pool mining, and see the differences between the two. The book will then walk you through large-scale mining and the challenges faced during such operations. Finally, you will take a look into the future to see a world where blockchain-based applications are commonplace and mining is ubiquitous.
Steef-Jan Wiggers
BizTalk enables the integration and managment of automated business processes within or across organizational boundaries. To build a solid BizTalk solution, deploy a robust environment, and keep it running smoothly you sometimes need to broaden your spectrum, explore all possibilities, and choose the best solution for your purpose. By following the recipes in this book you will gain required knowledge and succeed in your implementation.With BizTalk Server 2010 Cookbook, you can leverage and hone your skills. More than 50 recipes will guide you in implementing BizTalk solutions, setting up a robust and well performing BizTalk environment, and choosing the right solution for monitoring it. As a developer or administrator you greatly benefit from taking these recipes to work.In this book a developer and administrator will see how to deploy, build, and maintain a BizTalk environment. How to apply patterns for robust orchestrations, messaging and testing.Administrators will learn to set up an environment using Microsoft best practices and tools to deliver a robust, performing and durable BizTalk environment. Besides setting up their environments administrators can also decide through a number of recipes how to monitor and maintain the environment. A developer can contribute to a healthy environment by implementing instrumentation in artefacts, applying well suited pattern(s) and testing the solutions built.