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Ładowanie
Załadowano
Wystąpił nieokreślony błąd - spróbuj ponownie
Author: Grzegorz Grześk
1
Ebook
Finerenon to pierwszy niesteroidowy antagonista receptora dla mineralokortykoidów, który dzięki unikalnym właściwościom farmakologicznym charakteryzuje się potwierdzoną wynikami badań klinicznych wysoką efektywnością działania skojarzoną ze znikomą liczbą działań niepożądanych. W programie badań III fazy znajdowały się dwa kluczowe badania: FIDELIO-DKD (Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease) i FIGARO-DKD (Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease). Uczestniczyło w nich łącznie 13 171 osób z cukrzycową przewlekłą chorobą nerek (PChN) o różnym stopniu nasilenia. Ze względu na bardzo wysoką efektywność finerenon powinien być wdrażany w terapii u pacjentów z cukrzycą i PChN. Celem zastosowanego leczenia, poprzez hamowanie procesu zapalnego, jest nie tylko spowolnienie progresji PChN, ale także istotna redukcja ryzyka incydentów sercowo-naczyniowych. Terapia taka powinna być obowiązkowo rozpatrywana u pacjentów z PChN w przebiegu cukrzycy.